Mito Health: Helping you live healthier, longer.

In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.

Mito Health: Helping you live healthier, longer.

In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.

Mito Health: Helping you live healthier, longer.

In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.

Mito Health: Helping you live healthier, longer.

In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.

Mar 20, 2025

Omega-3 and Depression: Could Your Mood Swings Be a Nutrient Deficiency?

Emerging research links low omega-3 levels to anxiety, depression, and cognitive decline. If you’ve been feeling off, could the solution be as simple as adjusting your fat intake?

Written by

Yongzi See

You feel down, irritable, and lack motivation. You’ve tried everything, but nothing seems to work.

Could increasing your intake of omega-3 fatty acids be the cure?

TL;DR

  • Omega-3s, essential fats, are vital for brain health and function

  • Studies show a link between low omega-3 levels and an increased risk of depression

  • Increasing omega-3 intake through diet or supplements may improve mood and cognitive function

What are Omega-3 Fatty Acids?

__wf_reserved_inherit
  • Essential fats, crucial for brain health and function

  • Influence how neurons communicate

  • Possess anti-inflammatory properties, vital for mood regulation

  • Inflammation is increasingly linked to depression

Key Types of Omega-3s

  • EPA (Eicosapentaenoic Acid): Reduces inflammation

  • DHA (Docosahexaenoic Acid): Crucial for brain health, eyesight, and heart function

  • ALA (Alpha-Linolenic Acid): Primarily an energy source, inefficiently converted to EPA and DHA

The Omega-3 and Depression Connection

__wf_reserved_inherit

Your brain needs omega-3s, particularly EPA and DHA, to function correctly. 

Individuals experiencing depression may have insufficient levels of these essential fats.

This deficiency could disrupt brain cell communication, neurotransmitter production, and inflammatory responses, all of which play a role in mood regulation.  

What the Research Says

  • Reduced Risk of Depression: Individuals with higher levels of omega-3s, especially EPA, were less likely to experience major depressive disorder

  • Improved Mood and Cognition: Higher doses of omega-3s (~4 grams/day) can improve motivational symptoms and cognitive function in people with depression

  • Enhanced Antidepressant Effects: Omega-3 fatty acid supplements combined with antidepressants were more effective in alleviating depressive symptoms than antidepressants alone

How to Increase Omega-3 Intake

__wf_reserved_inherit

The best way to increase your omega-3 intake is through a balanced diet and supplementation.

Dietary Changes

  • Fatty Fish: Salmon, mackerel, tuna, herring, and sardines are excellent sources of EPA and DHA

  • Nuts and Seeds: Flaxseed, chia seeds, and walnuts are good sources of ALA

  • Plant Oils: Flaxseed oil, soybean oil, and canola oil contain ALA

Supplementation

  • Consider supplements if you struggle to get enough omega-3s through your diet

  • Different types of omega-3 supplements are available, including:







    • Natural Fish Oil  

    • Processed Fish Oil  

    • Krill Oil  

    • Green-Lipped Mussel Oil  

    • ALA Oil  

    • Cod Liver Oil  

    • Algal Oil 

Recommended Daily Intake of Omega-3s

The recommended daily intake of omega-3s varies depending on age, gender, and health status.

__wf_reserved_inherit

Conclusion

  • Omega-3 fatty acids, especially EPA, may play a significant role in mood regulation.  

  • Ensuring adequate omega-3 intake through diet or supplementation can support mental health.  

  • Schedule an OmegaCheck and consult a healthcare professional to determine the appropriate dosage and type of omega-3 for your needs.  

References

Get 10x the value for a fraction of the walk-in price

10x more value at a fraction of
the walk-in price.

Get 10x the value for a fraction of the walk-in price

Get 10x the value for a fraction of the walk-in price

Company

Inquire

Join our newsletter

The information provided by Mito Health is for improving your overall health and wellness only and is not intended to provide medical advice, diagnosis, or treatment. We engage the services of partner clinics authorised to order the tests and to receive your blood test results prior to making Mito Health analytics and recommendations available to you. These interactions are not intended to create, nor do they create, a doctor-patient relationship. You should seek the advice of a doctor or other qualified health provider with whom you have such a relationship if you are experiencing any symptoms of, or believe you may have, any medical or psychiatric condition. You should not ignore professional medical advice or delay in seeking it because of Mito Health recommendations or analysis. This service should not be used for medical diagnosis or treatment. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your clinician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your clinician or other qualified health provider.

© 2025 Mito Health Inc.

Company

Inquire

Join our newsletter

The information provided by Mito Health is for improving your overall health and wellness only and is not intended to provide medical advice, diagnosis, or treatment. We engage the services of partner clinics authorised to order the tests and to receive your blood test results prior to making Mito Health analytics and recommendations available to you. These interactions are not intended to create, nor do they create, a doctor-patient relationship. You should seek the advice of a doctor or other qualified health provider with whom you have such a relationship if you are experiencing any symptoms of, or believe you may have, any medical or psychiatric condition. You should not ignore professional medical advice or delay in seeking it because of Mito Health recommendations or analysis. This service should not be used for medical diagnosis or treatment. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your clinician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your clinician or other qualified health provider.

© 2025 Mito Health Inc.

Company

Inquire

Join our newsletter

The information provided by Mito Health is for improving your overall health and wellness only and is not intended to provide medical advice, diagnosis, or treatment. We engage the services of partner clinics authorised to order the tests and to receive your blood test results prior to making Mito Health analytics and recommendations available to you. These interactions are not intended to create, nor do they create, a doctor-patient relationship. You should seek the advice of a doctor or other qualified health provider with whom you have such a relationship if you are experiencing any symptoms of, or believe you may have, any medical or psychiatric condition. You should not ignore professional medical advice or delay in seeking it because of Mito Health recommendations or analysis. This service should not be used for medical diagnosis or treatment. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your clinician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your clinician or other qualified health provider.

© 2025 Mito Health Inc.

Company

Inquire

Join our newsletter

The information provided by Mito Health is for improving your overall health and wellness only and is not intended to provide medical advice, diagnosis, or treatment. We engage the services of partner clinics authorised to order the tests and to receive your blood test results prior to making Mito Health analytics and recommendations available to you. These interactions are not intended to create, nor do they create, a doctor-patient relationship. You should seek the advice of a doctor or other qualified health provider with whom you have such a relationship if you are experiencing any symptoms of, or believe you may have, any medical or psychiatric condition. You should not ignore professional medical advice or delay in seeking it because of Mito Health recommendations or analysis. This service should not be used for medical diagnosis or treatment. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your clinician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your clinician or other qualified health provider.

© 2025 Mito Health Inc.