Your guide to Alanine Transaminase (ALT).
Understand the role of Alanine Transaminase (ALT) in your health and longevity with Mito Health's comprehensive biomarker analysis. Our detailed reports cover key biomarkers, providing essential insights to help you make informed decisions for a healthier, longer life.
What is Alanine Transaminase (ALT)?
Alanine transaminase (ALT), also known as serum glutamate-pyruvate transaminase (SGPT), is an enzyme found primarily in the liver.
Smaller amounts are also found in the kidneys, heart, muscles, and pancreas.
What does it assess?
Irritation or damage to liver cells results in release of ALT in the blood. ALT levels are thus used as a key marker of liver health.
How do I optimize my Alanine Transaminase (ALT) levels?
A balanced diet low in saturated fats, refined sugars, and processed foods can help prevent liver fat buildup and reduce ALT levels. Prioritize foods rich in antioxidants and anti-inflammatory properties, such as leafy greens, berries, whole grains, and fatty fish (rich in omega-3s).
Additionally, fiber-rich foods, like vegetables and whole grains, help support overall liver function.
Excessive alcohol consumption can raise ALT levels and strain liver health. To keep ALT levels within the optimal range, consider minimizing alcohol intake or eliminating it entirely.
Conditions like diabetes, high cholesterol, and hypertension can affect liver health and ALT levels.
Effectively managing these conditions through diet, lifestyle changes, and medication as needed can help maintain a healthy ALT level.
What do high and low Alanine Transaminase (ALT) levels mean?
Elevated ALT levels in the blood typically indicates damage to liver cells. This can be due to recent illness (eg. viral infections), alcohol intake or certain medications.
If persistently elevated, this is typically of more concern, and can be due to any chronic inflammation or scarring of the liver from hepatitis infection, alcohol consumption and metabolic-associated fatty liver disease.
Low levels of alanine transaminase are generally not a cause for concern and typically indicate healthy liver function. At extremely low levels, this is sometimes seen in malnutrition and chronic disease.