Your guide to Total Prostate Specific Antigen (PSA).
Discover the role of Total Prostate Specific Antigen (PSA) in your health and longevity with Mito Health's advanced biomarker analysis. Our detailed reports cover key biomarkers, providing essential insights to help you make informed decisions for a healthier, longer life.
What is Total Prostate Specific Antigen (PSA)?
Prostate specific antigen (PSA) is a protein that is normally released in small amounts from the prostate gland. As men age, PSA levels often rise gradually in response to increasing prostate size (hypertrophy).
However, elevated levels or rapidly increasing levels of PSA detected also occur in prostate inflammation and cancer. When interpreting this result, it is important to note the absolute value and, more importantly, the rate of change from previously.
Note that medications such as finasteride for hair loss that affect testosterone and DHT can falsely lower PSA levels and monitoring rate of change becomes even more important if you are on this medication.
What does it assess?
Prostate Specific Antigen (PSA) is a protein produced by the prostate gland and measured in the blood to assess prostate health. PSA testing is primarily used to screen for prostate cancer, as elevated levels may indicate cancerous or benign conditions like benign prostatic hyperplasia (BPH) or prostatitis (prostate inflammation). Monitoring PSA levels helps in evaluating cancer risk, tracking treatment progress, and identifying potential recurrence of prostate cancer.
How do I optimize my PSA levels?
A diet rich in fruits, vegetables, and healthy fats can help reduce inflammation, potentially supporting prostate health. Foods like tomatoes, cruciferous vegetables, and pomegranate have shown possible benefits for prostate health in some studies.
High saturated fat intake and excessive consumption of processed foods have been associated with increased risk of prostate health issues. Opt for healthier fats like those in olive oil, nuts, and avocados.
Excessive alcohol and tobacco can negatively impact prostate health. Limiting or avoiding these can support PSA optimization and general prostate health.
What do high and low levels of PSA mean?
Elevated PSA levels can indicate an increased risk of prostate cancer, though they are not definitive for diagnosis. High levels may also reflect benign conditions such as BPH or prostatitis, especially in older men. Persistent elevation often warrants further testing, such as a biopsy, to rule out or confirm cancer.
Low or normal PSA levels are generally a positive indicator of prostate health, suggesting an absence of significant prostate abnormalities. However, PSA levels naturally increase with age, so what’s considered "normal" can vary depending on an individual's age and overall health.
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