Peter Attia's Supplement Routine: A Science-Driven Approach to Longevity

Discover Peter Attia’s science-backed supplement routine, designed to enhance longevity, reduce inflammation, and support overall health through a personalized approach.

Written By
Gabriel Tan
January 15, 2025

TLDR;

  • Philosophy: Peter Attia emphasizes evidence-based supplementation to support longevity.
  • Key Supplements: Omega-3s, Vitamin D3 and K2, Magnesium, NR, Curcumin, Probiotics, and Creatine.
  • Benefits: These supplements target inflammation, cognitive function, bone health, and mitochondrial support.
  • Personalization: Attia advocates for tailored supplementation based on individual needs and regular health assessments

Peter Attia, a renowned physician focusing on longevity and optimal health, has curated a supplement routine grounded in scientific research. His approach emphasizes preventing chronic illnesses, enhancing cognitive function, and maintaining peak physical performance.

This article delves into the supplements Peter Attia includes in his regimen, explains the rationale behind them, and explores how they align with his philosophy of proactive health management.

The Philosophy Behind the Supplementation

Peter Attia’s supplement routine reflects his commitment to precision medicine. His approach involves leveraging supplements for specific health outcomes, such as reducing inflammation, supporting mitochondrial health, and optimizing brain function.

While Attia emphasizes that supplements are no substitute for a nutrient-rich diet, regular exercise, and good sleep hygiene, he acknowledges their role in filling nutritional gaps and addressing individual health needs.

Key Supplements in Peter Attia's Routine

1. Omega-3 Fatty Acids
Omega-3s, particularly EPA and DHA, support heart health, reduce systemic inflammation, and promote cognitive function.

Research highlights that omega-3 supplementation reduces the risk of cardiovascular disease and supports brain health.

2. Vitamin D3 and K2
These vitamins work synergistically to maintain bone health, support immune function, and regulate calcium metabolism.

Studies show that adequate vitamin D levels are linked to reduced risks of osteoporosis and autoimmune diseases. Vitamin K2 helps ensure calcium is directed to bones rather than arteries, reducing calcification risks.

3. Magnesium
Magnesium supports over 300 enzymatic processes, including muscle function, sleep regulation, and cardiovascular health.

Magnesium supplementation improves sleep quality and reduces symptoms of anxiety and muscle cramp.

4.Nicotinamide Riboside (NR)
NR boosts NAD+ levels, crucial for cellular energy production and DNA repair.

Studies suggest that increasing NAD+ can slow the aging process and enhance mitochondrial function.

5. Curcumin
This bioactive compound in turmeric combats inflammation and supports joint health.

Curcumin has demonstrated anti-inflammatory and antioxidant properties, making it a valuable supplement for managing chronic inflammatory conditions.

6. Probiotics
Probiotics improve gut health, which is integral to immune function, mood, and overall health.

A balanced gut microbiome is associated with reduced inflammation and improved digestion.

7. Creatine
Creatine is commonly associated with athletic performance, creatine also supports cognitive function and muscle preservation.

Creatine supplementation has been linked to improved memory and reduced muscle loss during aging.

Why a Personalized Approach Matters

Peter Attia emphasizes that supplementation should be tailored to individual needs.

Factors like genetics, diet, lifestyle, and specific health concerns influence which supplements are most beneficial. Attia also advocates for regular testing to ensure supplements are effective and necessary.

Cautions and Considerations

While supplements can provide significant health benefits, they must be used wisely.

Attia underscores the importance of consulting with healthcare professionals before starting any supplement regimen to avoid potential interactions or side effects.

Conclusion

Peter Attia’s supplement routine underscores his commitment to longevity and optimized health through evidence-based practices.

His strategic use of supplements highlights the importance of addressing individual health needs, supporting the body’s natural processes, and preventing chronic diseases.

References
  • Abbasi, B., Kimiagar, M., Sadeghniiat, K., Shirazi, M. M., Hedayati, M., & Rashidkhani, B. (2012). The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. Journal of Research in Medical Sciences, 17(12), 1161–1169.
  • Gupta, S. C., Patchva, S., & Aggarwal, B. B. (2013). Therapeutic roles of curcumin: lessons learned from clinical trials. The AAPS Journal, 15(1), 195–218.
  • Holick, M. F. (2007). Vitamin D deficiency. New England Journal of Medicine, 357(3), 266–281.
  • Kreider, R. B., Kalman, D. S., Antonio, J., Ziegenfuss, T. N., Wildman, R., Collins, R., & Lopez, H. L. (2017). International society of sports nutrition position stand: Safety and efficacy of creatine supplementation in exercise, sport, and medicine. Journal of the International Society of Sports Nutrition, 14(1), 18.
  • Mozaffarian, D., & Wu, J. H. (2011). Omega-3 fatty acids and cardiovascular disease: Effects on risk factors, molecular pathways, and clinical events. Journal of the American College of Cardiology, 58(20), 2047–2067.
  • Ouwehand, A. C., Salminen, S., & Isolauri, E. (2002). Probiotic and other functional microbes: From markets to mechanisms. Current Opinion in Biotechnology, 13(5), 483–487.
  • Rajman, L., Chwalek, K., & Sinclair, D. A. (2018). Therapeutic potential of NAD-boosting molecules: The in vivo evidence. Cell Metabolism, 27(3), 529–547.
  • Schurgers, L. J., Teunissen, K. J. F., Hamulyać, J. T., Knapen, M. H. J., Vik, H., & Vermeer, C. (2007). Vitamin K-containing dietary supplements: Comparison of synthetic vitamin K1 and natto-derived menaquinone-7. Blood, 109(8), 3279–3283.

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