Mito Health: Helping you live healthier, longer.

In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.

Mito Health: Helping you live healthier, longer.

In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.

Mito Health: Helping you live healthier, longer.

In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.

Mito Health: Helping you live healthier, longer.

In-depth bloodwork & holistic health advice, backed by the latest longevity science. Only $399.

Mar 20, 2025

Peter Attia's Supplement Routine: A Science-Driven Approach to Longevity

Discover Peter Attia’s science-backed supplement routine, designed to enhance longevity, reduce inflammation, and support overall health through a personalized approach.

TLDR;

  • Philosophy: Peter Attia emphasizes evidence-based longevity supplements.

  • Key Supplements: Omega-3s, Vitamin D3 and K2, Magnesium, NR, Curcumin, Probiotics, Creatine.

  • Benefits: Help with inflammation, vitamin K2 benefits, cognitive health, and mitochondrial support.

  • Personalization: Attia recommends testing before taking vitamin D and K2 supplements.

Curious about Peter Attia’s supplement routine? His science-backed regimen includes Vitamin D3 and K2, omega-3s, magnesium, curcumin, and other key nutrients that support longevity and reduce inflammation. Learn how these vitamins and supplements work together to optimize long-term health.

This article delves into the supplements Peter Attia includes in his regimen, explains the rationale behind them, and explores how they align with his philosophy of proactive health management.

The Philosophy Behind the Supplementation

Peter Attia’s supplement routine reflects his commitment to precision medicine. His approach involves leveraging supplements for specific health outcomes, such as reducing inflammation, supporting mitochondrial health, and optimizing brain function.

While Attia emphasizes that supplements are no substitute for a nutrient-rich diet, regular exercise, and good sleep hygiene, he acknowledges their role in filling nutritional gaps and addressing individual health needs.

Peter Attia Supplements: Vitamin D3, K2, and Other Longevity Essentials

1. Omega-3 Fatty Acids
Omega-3s, particularly EPA and DHA, support heart health, reduce systemic inflammation, and promote cognitive function.

Research highlights that omega-3 supplementation reduces the risk of cardiovascular disease and supports brain health.

For a deeper understanding of how Dr. Attia manages cardiovascular health, including his strategies to lower apoB levels, explore his approach to heart health.

2. Vitamin D3 and K2
These vitamins work synergistically to maintain bone health, support immune function, and regulate calcium metabolism.

Studies show that adequate vitamin D levels are linked to reduced risks of osteoporosis and autoimmune diseases. Vitamin K2 helps ensure calcium is directed to bones rather than arteries, reducing calcification risks.

The combined use of Vitamin D3 and K2 supports calcium metabolism, bone health, and cardiovascular health. Taking Vitamin D with K2 ensures calcium is delivered to bones, not arteries—lowering the risk of arterial calcification and boosting overall vitality.

3. Magnesium
Magnesium supports over 300 enzymatic processes, including muscle function, sleep regulation, and cardiovascular health.

Magnesium supplementation improves sleep quality and reduces symptoms of anxiety and muscle cramp.

4.Nicotinamide Riboside (NR)
NR boosts NAD+ levels, crucial for cellular energy production and DNA repair.

Studies suggest that increasing NAD+ can slow the aging process and enhance mitochondrial function.

5. Curcumin
This bioactive compound in turmeric combats inflammation and supports joint health.

Curcumin has demonstrated anti-inflammatory and antioxidant properties, making it a valuable supplement for managing chronic inflammatory conditions.

6. Probiotics
Probiotics improve gut health, which is integral to immune function, mood, and overall health.

A balanced gut microbiome is associated with reduced inflammation and improved digestion.

7. Creatine
Creatine is commonly associated with athletic performance, creatine also supports cognitive function and muscle preservation.

Creatine supplementation has been linked to improved memory and reduced muscle loss during aging.

Vitamin D3 and K2 Benefits for Longevity

Combining Vitamin D3 and K2 offers powerful longevity benefits. Studies suggest this combo helps regulate calcium levels, protect the heart, and improve immune function.

  • Vitamin K2 benefits include directing calcium to bones and teeth, preventing arterial plaque.‍

  • Vitamin D3 supports hormone balance, energy production, and mood regulation.

These two vitamins work synergistically and are among the most recommended by experts like Peter Attia for healthy aging.

Always consult a healthcare professional before taking any **Vitamin D3 & K2 supplement**, especially if you’re on medication or have underlying conditions.

Why a Personalized Approach Matters

Peter Attia emphasizes that supplementation should be tailored to individual needs.

Factors like genetics, diet, lifestyle, and specific health concerns influence which supplements are most beneficial. Attia also advocates for regular testing to ensure supplements are effective and necessary.

Cautions and Considerations

While supplements can provide significant health benefits, they must be used wisely.

Attia underscores the importance of consulting with healthcare professionals before starting any supplement regimen to avoid potential interactions or side effects.

Conclusion

Peter Attia’s supplement routine underscores his commitment to longevity and optimized health through evidence-based practices.

His strategic use of supplements highlights the importance of addressing individual health needs, supporting the body’s natural processes, and preventing chronic diseases.

From Vitamin D3 & K2 to curcumin and magnesium, these carefully selected supplements reflect his evidence-driven philosophy for aging well. To learn more about the synergy of Vitamin D and K2, and how they support your long-term health, consult with your provider or explore high-quality supplement options tailored to your needs.

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The information provided by Mito Health is for improving your overall health and wellness only and is not intended to provide medical advice, diagnosis, or treatment. We engage the services of partner clinics authorised to order the tests and to receive your blood test results prior to making Mito Health analytics and recommendations available to you. These interactions are not intended to create, nor do they create, a doctor-patient relationship. You should seek the advice of a doctor or other qualified health provider with whom you have such a relationship if you are experiencing any symptoms of, or believe you may have, any medical or psychiatric condition. You should not ignore professional medical advice or delay in seeking it because of Mito Health recommendations or analysis. This service should not be used for medical diagnosis or treatment. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your clinician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your clinician or other qualified health provider.

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© 2025 Mito Health Inc.

Company

Join our newsletter

The information provided by Mito Health is for improving your overall health and wellness only and is not intended to provide medical advice, diagnosis, or treatment. We engage the services of partner clinics authorised to order the tests and to receive your blood test results prior to making Mito Health analytics and recommendations available to you. These interactions are not intended to create, nor do they create, a doctor-patient relationship. You should seek the advice of a doctor or other qualified health provider with whom you have such a relationship if you are experiencing any symptoms of, or believe you may have, any medical or psychiatric condition. You should not ignore professional medical advice or delay in seeking it because of Mito Health recommendations or analysis. This service should not be used for medical diagnosis or treatment. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your clinician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your clinician or other qualified health provider.

Terms of service

Privacy policy

© 2025 Mito Health Inc.

Company

Join our newsletter

The information provided by Mito Health is for improving your overall health and wellness only and is not intended to provide medical advice, diagnosis, or treatment. We engage the services of partner clinics authorised to order the tests and to receive your blood test results prior to making Mito Health analytics and recommendations available to you. These interactions are not intended to create, nor do they create, a doctor-patient relationship. You should seek the advice of a doctor or other qualified health provider with whom you have such a relationship if you are experiencing any symptoms of, or believe you may have, any medical or psychiatric condition. You should not ignore professional medical advice or delay in seeking it because of Mito Health recommendations or analysis. This service should not be used for medical diagnosis or treatment. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your clinician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your clinician or other qualified health provider.

Terms of service

Privacy policy

© 2025 Mito Health Inc.

Company

Join our newsletter

The information provided by Mito Health is for improving your overall health and wellness only and is not intended to provide medical advice, diagnosis, or treatment. We engage the services of partner clinics authorised to order the tests and to receive your blood test results prior to making Mito Health analytics and recommendations available to you. These interactions are not intended to create, nor do they create, a doctor-patient relationship. You should seek the advice of a doctor or other qualified health provider with whom you have such a relationship if you are experiencing any symptoms of, or believe you may have, any medical or psychiatric condition. You should not ignore professional medical advice or delay in seeking it because of Mito Health recommendations or analysis. This service should not be used for medical diagnosis or treatment. The recommendations contained herein are not intended to diagnose, treat, cure or prevent any disease. You should always consult your clinician or other qualified health provider before starting any new treatment or stopping any treatment that has been prescribed for you by your clinician or other qualified health provider.

Terms of service

Privacy policy

© 2025 Mito Health Inc.